Spatially restricted activation of RhoA at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

Signalling by the GTPase RhoA, a key regulator of epithelial cell behaviour, can stimulate opposing processes: RhoA can promote junction formation and apical constriction, as well as reduced adhesion and cell spreading1, 2. Molecular mechanisms are thus required that ensure spatially restricted and...

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Detalles Bibliográficos
Autores principales: Terry, Stephen J., Zihni, Ceniz, Elbediwy, Ahmed, Vitiello, Elisa, San, Isabelle V. Leefa Chong, Balda, Maria S., Matter, Karl
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032653/
https://www.ncbi.nlm.nih.gov/pubmed/21258369
http://dx.doi.org/10.1038/ncb2156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032653/
https://www.ncbi.nlm.nih.gov/pubmed/21258369
http://dx.doi.org/10.1038/ncb2156

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