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Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study

BACKGROUND: Adiponectin, secreted mainly by mature adipocytes, is a protein with insulin-sensitising and anti-atherogenic effects. Human adiponectin is encoded by the ADIPOQ gene on the chromosomal locus 3q27. Variations in ADIPOQ are associated with obesity, type 2 diabetes (T2DM) and related pheno...

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Detalles Bibliográficos
Autores principales: Siitonen, Niina, Pulkkinen, Leena, Lindström, Jaana, Kolehmainen, Marjukka, Eriksson, Johan G, Venojärvi, Mika, Ilanne-Parikka, Pirjo, Keinänen-Kiukaanniemi, Sirkka, Tuomilehto, Jaakko, Uusitupa, Matti
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032655/
https://www.ncbi.nlm.nih.gov/pubmed/21219602
http://dx.doi.org/10.1186/1471-2350-12-5