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Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolution

BACKGROUND: New high-throughput sequencing technologies promise a very sensitive and high-resolution analysis of DNA methylation patterns in quantitative terms. However, a detailed and comprehensive comparison with existing validated DNA methylation analysis methods is not yet available. Therefore,...

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Detalles Bibliográficos
Autores principales: Potapova, Anna, Albat, Cord, Hasemeier, Britta, Haeussler, Katrin, Lamprecht, Stella, Suerbaum, Sebastian, Kreipe, Hans, Lehmann, Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032674/
https://www.ncbi.nlm.nih.gov/pubmed/21235780
http://dx.doi.org/10.1186/1472-6750-11-6