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Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents
BACKGROUND: Protein and mRNA levels for several selenoproteins, such as glutathione peroxidase-1 (Gpx1), are down-regulated dramatically by selenium (Se) deficiency. These levels in rats increase sigmoidally with increasing dietary Se and reach defined plateaus at the Se requirement, making them sen...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032699/ https://www.ncbi.nlm.nih.gov/pubmed/21226930 http://dx.doi.org/10.1186/1471-2164-12-26 |