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Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast

BACKGROUND: The ubiquitin(Ub)-proteasome pathway is implicated in the regulation of a variety of cellular functions and plays a major role in stress response in eukaryotic cells, by targeting misfolded and damaged proteins for degradation. In addition, in the presence of DNA damage, the Ub-proteasom...

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Detalles Bibliográficos
Autores principales: Gatti, Laura, Hoe, Kwang L, Hayles, Jacqueline, Righetti, Sabina C, Carenini, Nives, Bo, Laura Dal, Kim, Dong U, Park, Han O, Perego, Paola
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032702/
https://www.ncbi.nlm.nih.gov/pubmed/21247416
http://dx.doi.org/10.1186/1471-2164-12-44