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Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of coxsackievirus b3-induced viral myocarditis reduces myocardium inflammation

BACKGROUND: Recently, some studies indicate that interleukin (IL)-17, known as a T cell (Th17)-derived proinflammatory cytokine, is the major mediator of tissue inflammation in inflammatory and autoimmune diseases. Viral myocarditis (VMC) is a T cell-mediated autoimmune disease, but the role for IL-...

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Detalles Bibliográficos
Autores principales: Fan, Yang, Weifeng, Wu, Yuluan, Yan, Qing, Kong, Yu, Pang, Yanlan, Huang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032710/
https://www.ncbi.nlm.nih.gov/pubmed/21235788
http://dx.doi.org/10.1186/1743-422X-8-17