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Characterization of thiobarbituric acid derivatives as inhibitors of hepatitis C virus NS5B polymerase
In an effort to find chemicals inhibiting the enzymatic activity of the hepatitis C virus (HCV) NS5B polymerase, a series of thiobarbituric acid derivatives were selected from a library provided by Korea Research Institute of Chemical Technology and characterized. The selected compounds exhibited IC...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032711/ https://www.ncbi.nlm.nih.gov/pubmed/21235805 http://dx.doi.org/10.1186/1743-422X-8-18 |