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Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice

BACKGROUND: Sphingomyelin synthase 2 (SMS2) contributes to de novo sphingomyelin (SM) biosynthesis. Its activity is related to SM levels in the plasma and the cell membrane. In this study, we investigated the possibility of a direct relationship between SMS and atherosclerosis. METHODS: The Adenovir...

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Detalles Bibliográficos
Autores principales: Wang, Xiaogang, Dong, Jibin, Zhao, Yarui, Li, Yue, Wu, Manping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032723/
https://www.ncbi.nlm.nih.gov/pubmed/21235823
http://dx.doi.org/10.1186/1476-511X-10-7