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Activation of the hedgehog pathway in chronic myelogeneous leukemia patients

BACKGROUND: Hedgehog (Hh) signaling pathway is involved in regulation of many tissues development and oncogenesis. Recently, Hh signaling has been identified as a required functional pathway for leukemia stem cells(LSCs), and loss of this pathway impairs leukemia progression. OBJECTIVES: The aim of...

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Detalles Bibliográficos
Autores principales: Long, Bing, Zhu, Huanling, Zhu, Cuixia, Liu, Ting, Meng, Wentong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032744/
https://www.ncbi.nlm.nih.gov/pubmed/21235817
http://dx.doi.org/10.1186/1756-9966-30-8