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Activation of the hedgehog pathway in chronic myelogeneous leukemia patients
BACKGROUND: Hedgehog (Hh) signaling pathway is involved in regulation of many tissues development and oncogenesis. Recently, Hh signaling has been identified as a required functional pathway for leukemia stem cells(LSCs), and loss of this pathway impairs leukemia progression. OBJECTIVES: The aim of...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032744/ https://www.ncbi.nlm.nih.gov/pubmed/21235817 http://dx.doi.org/10.1186/1756-9966-30-8 |