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ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence

BACKGROUND: Mounting evidence has indicated that ABI3 (ABI family member 3) function as a tumor suppressor gene, although the molecular mechanism by which ABI3 acts remains largely unknown. METHODS: The present study investigated ABI3 expression in a large panel of benign and malignant thyroid tumor...

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Detalles Bibliográficos
Autores principales: Latini, Flavia RM, Hemerly, Jefferson P, Freitas, Beatriz CG, Oler, Gisele, Riggins, Gregory J, Cerutti, Janete M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032749/
https://www.ncbi.nlm.nih.gov/pubmed/21223585
http://dx.doi.org/10.1186/1471-2407-11-11