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Retinoblastoma-independent antiproliferative activity of novel intracellular antibodies against the E7 oncoprotein in HPV 16-positive cells

BACKGROUND: "High risk" Human Papillomavirus strains are the causative agents of the vast majority of carcinomas of the uterine cervix. In these tumors, the physical integration of the HPV genome is a frequent, though not invariable occurrence, but the constitutive expression of the E6 and...

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Detalles Bibliográficos
Autores principales: Accardi, Luisa, Donà, Maria Gabriella, Mileo, Anna M, Paggi, Marco G, Federico, Antonio, Torreri, Paola, Petrucci, Tamara C, Accardi, Rosita, Pim, David, Tommasino, Massimo, Banks, Lawrence, Chirullo, Barbara, Giorgi, Colomba
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032750/
https://www.ncbi.nlm.nih.gov/pubmed/21241471
http://dx.doi.org/10.1186/1471-2407-11-17