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Zebrafish as a Model System to Study the Physiological Function of Telomeric Protein TPP1

Telomeres are specialized chromatin structures at the end of chromosomes. Telomere dysfunction can lead to chromosomal abnormalities, DNA damage responses, and even cancer. In mammalian cells, a six-protein complex (telosome/shelterin) is assembled on the telomeres through the interactions between v...

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Detalles Bibliográficos
Autores principales: Xie, Yiying, Yang, Dong, He, Quanyuan, Songyang, Zhou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032778/
https://www.ncbi.nlm.nih.gov/pubmed/21311760
http://dx.doi.org/10.1371/journal.pone.0016440