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Zebrafish as a Model System to Study the Physiological Function of Telomeric Protein TPP1
Telomeres are specialized chromatin structures at the end of chromosomes. Telomere dysfunction can lead to chromosomal abnormalities, DNA damage responses, and even cancer. In mammalian cells, a six-protein complex (telosome/shelterin) is assembled on the telomeres through the interactions between v...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032778/ https://www.ncbi.nlm.nih.gov/pubmed/21311760 http://dx.doi.org/10.1371/journal.pone.0016440 |