DNA Polymerase β as a Novel Target for Chemotherapeutic Intervention of Colorectal Cancer

Chemoprevention presents a major strategy for the medical management of colorectal cancer. Most drugs used for colorectal cancer therapy induce DNA-alkylation damage, which is primarily repaired by the base excision repair (BER) pathway. Thus, blockade of BER pathway is an attractive option to inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaiswal, Aruna S., Banerjee, Sanjeev, Aneja, Ritu, Sarkar, Fazlul H., Ostrov, David A., Narayan, Satya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032781/
https://www.ncbi.nlm.nih.gov/pubmed/21311763
http://dx.doi.org/10.1371/journal.pone.0016691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032781/
https://www.ncbi.nlm.nih.gov/pubmed/21311763
http://dx.doi.org/10.1371/journal.pone.0016691

Ejemplares similares