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DNA Polymerase β as a Novel Target for Chemotherapeutic Intervention of Colorectal Cancer

Chemoprevention presents a major strategy for the medical management of colorectal cancer. Most drugs used for colorectal cancer therapy induce DNA-alkylation damage, which is primarily repaired by the base excision repair (BER) pathway. Thus, blockade of BER pathway is an attractive option to inhib...

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Detalles Bibliográficos
Autores principales:	Jaiswal, Aruna S., Banerjee, Sanjeev, Aneja, Ritu, Sarkar, Fazlul H., Ostrov, David A., Narayan, Satya
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032781/ https://www.ncbi.nlm.nih.gov/pubmed/21311763 http://dx.doi.org/10.1371/journal.pone.0016691

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