Epithelial Tissues Have Varying Degrees of Susceptibility to Kras(G12D)-Initiated Tumorigenesis in a Mouse Model

Activating mutations in the Kras gene are commonly found in some but not all epithelial cancers. In order to understand the susceptibility of different epithelial tissues to Kras-induced tumorigenesis, we introduced one of the most common Kras mutations, Kras(G12D), broadly in epithelial tissues. We...

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Detalles Bibliográficos
Autores principales: Ray, Kevin C., Bell, Kayla M., Yan, Jingbo, Gu, Guoqiang, Chung, Christine H., Washington, M. Kay, Means, Anna L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032792/
https://www.ncbi.nlm.nih.gov/pubmed/21311774
http://dx.doi.org/10.1371/journal.pone.0016786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032792/
https://www.ncbi.nlm.nih.gov/pubmed/21311774
http://dx.doi.org/10.1371/journal.pone.0016786

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