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Epithelial Tissues Have Varying Degrees of Susceptibility to Kras(G12D)-Initiated Tumorigenesis in a Mouse Model
Activating mutations in the Kras gene are commonly found in some but not all epithelial cancers. In order to understand the susceptibility of different epithelial tissues to Kras-induced tumorigenesis, we introduced one of the most common Kras mutations, Kras(G12D), broadly in epithelial tissues. We...
Autores principales: | Ray, Kevin C., Bell, Kayla M., Yan, Jingbo, Gu, Guoqiang, Chung, Christine H., Washington, M. Kay, Means, Anna L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032792/ https://www.ncbi.nlm.nih.gov/pubmed/21311774 http://dx.doi.org/10.1371/journal.pone.0016786 |
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