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Megalin/LRP2 Expression Is Induced by Peroxisome Proliferator-Activated Receptor -Alpha and -Gamma: Implications for PPARs' Roles in Renal Function

BACKGROUND: Megalin is a large endocytic receptor with relevant functions during development and adult life. It is expressed at the apical surface of several epithelial cell types, including proximal tubule cells (PTCs) in the kidney, where it internalizes apolipoproteins, vitamins and hormones with...

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Detalles Bibliográficos
Autores principales: Cabezas, Felipe, Lagos, Jonathan, Céspedes, Carlos, Vio, Carlos P., Bronfman, Miguel, Marzolo, María-Paz
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032793/
https://www.ncbi.nlm.nih.gov/pubmed/21311715
http://dx.doi.org/10.1371/journal.pone.0016794