Cargando…

Impact of Alu repeats on the evolution of human p53 binding sites

BACKGROUND: The p53 tumor suppressor protein is involved in a complicated regulatory network, mediating expression of ~1000 human genes. Recent studies have shown that many p53 in vivo binding sites (BSs) reside in transposable repeats. The relationship between these BSs and functional p53 response...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Feng, Sirotin, Michael V, Zhurkin, Victor B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032802/
https://www.ncbi.nlm.nih.gov/pubmed/21208455
http://dx.doi.org/10.1186/1745-6150-6-2