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The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study

Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin β cytoplasmic tail. Here, we use coarse-grained molecular dynamic simulations and nuclear magnetic resonance spectrosco...

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Detalles Bibliográficos
Autores principales: Kalli, Antreas C., Wegener, Kate L., Goult, Benjamin T., Anthis, Nicholas J., Campbell, Iain D., Sansom, Mark S.P.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032884/
https://www.ncbi.nlm.nih.gov/pubmed/20947017
http://dx.doi.org/10.1016/j.str.2010.07.012