Conserved expression and functions of PDE4 in rodent and human heart

PDE4 isoenzymes are critical in the control of cAMP signaling in rodent cardiac myocytes. Ablation of PDE4 affects multiple key players in excitation–contraction coupling and predisposes mice to the development of heart failure. As little is known about PDE4 in human heart, we explored to what exten...

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Detalles Bibliográficos
Autores principales: Richter, Wito, Xie, Moses, Scheitrum, Colleen, Krall, Judith, Movsesian, Matthew A., Conti, Marco
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032896/
https://www.ncbi.nlm.nih.gov/pubmed/21161247
http://dx.doi.org/10.1007/s00395-010-0138-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032896/
https://www.ncbi.nlm.nih.gov/pubmed/21161247
http://dx.doi.org/10.1007/s00395-010-0138-8

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