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Cardiac Function and Iron Chelation in Thalassemia Major and Intermedia: a Review of the Underlying Pathophysiology and Approach to Chelation Management

Heart disease is the leading cause of mortality and one of the main causes of morbidity in beta-thalassemia. Patients with homozygous thalassemia may have either a severe phenotype which is usually transfusion dependent or a milder form that is thalassemia intermedia. The two main factors that deter...

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Detalles Bibliográficos
Autores principales: Aessopos, Athanasios, Berdoukas, Vasilios
Formato: Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033159/
https://www.ncbi.nlm.nih.gov/pubmed/21415984
http://dx.doi.org/10.4084/MJHID.2009.002