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Cardiac Function and Iron Chelation in Thalassemia Major and Intermedia: a Review of the Underlying Pathophysiology and Approach to Chelation Management
Heart disease is the leading cause of mortality and one of the main causes of morbidity in beta-thalassemia. Patients with homozygous thalassemia may have either a severe phenotype which is usually transfusion dependent or a milder form that is thalassemia intermedia. The two main factors that deter...
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Formato: | Texto |
Lenguaje: | English |
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Università Cattolica del Sacro Cuore
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033159/ https://www.ncbi.nlm.nih.gov/pubmed/21415984 http://dx.doi.org/10.4084/MJHID.2009.002 |