A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-wide association studies

BACKGROUND: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1 million genetic markers) and its complexity make the statistical analysis a challenging task. RESULTS: We present an acc...

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Detalles Bibliográficos
Autores principales: Mourad, Raphaël, Sinoquet, Christine, Leray, Philippe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033325/
https://www.ncbi.nlm.nih.gov/pubmed/21226914
http://dx.doi.org/10.1186/1471-2105-12-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033325/
https://www.ncbi.nlm.nih.gov/pubmed/21226914
http://dx.doi.org/10.1186/1471-2105-12-16

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