Cargando…

Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease

BACKGROUND: Complement proteins and activation products have been found associated with neuropathology in Alzheimer's disease (AD). Recently, a C5a receptor antagonist was shown to suppress neuropathology in two murine models of AD, Tg2576 and 3xTg. Previously, a genetic deficiency of C1q in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fonseca, Maria I, Chu, Shu-Hui, Berci, Alisia M, Benoit, Marie E, Peters, Douglas G, Kimura, Yuko, Tenner, Andrea J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033336/ https://www.ncbi.nlm.nih.gov/pubmed/21235806 http://dx.doi.org/10.1186/1742-2094-8-4

Ejemplares similares

Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer’s mouse models
por: Petrisko, Tiffany J., et al.
Publicado: (2023)

Alzheimer disease models and human neuropathology: similarities and differences
por: Duyckaerts, Charles, et al.
Publicado: (2007)

Neurogenesis Makes a Crucial Contribution to the Neuropathology of Alzheimer’s Disease
por: Young, John K.
Publicado: (2020)

The neuropathological diagnosis of Alzheimer’s disease
por: DeTure, Michael A., et al.
Publicado: (2019)

Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development
por: Rabinovici, Gil D., et al.
Publicado: (2016)

Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer’s Disease
por: Braun, David J., et al.
Publicado: (2017)

Renal Contributions in the Pathophysiology and Neuropathological Substrates Shared by Chronic Kidney Disease and Alzheimer’s Disease
por: Stanciu, Gabriela Dumitrita, et al.
Publicado: (2020)

Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics
por: Esposito, Michelle, et al.
Publicado: (2019)

Illustrated Neuropathologic Diagnosis of Alzheimer’s Disease
por: Doher, Nicholas, et al.
Publicado: (2023)

Triptolide Preserves Cognitive Function and Reduces Neuropathology in a Mouse Model of Alzheimer's Disease
por: Cheng, Shaowu, et al.
Publicado: (2014)

Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model
por: Flores, Joseph, et al.
Publicado: (2018)

Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines
por: Keene, C. Dirk, et al.
Publicado: (2016)

Magnolol Ameliorates Behavioral Impairments and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
por: Xian, Yan-Fang, et al.
Publicado: (2020)

Metabolic, Phenotypic, and Neuropathological Characterization of the Tg4-42 Mouse Model for Alzheimer’s Disease
por: Hinteregger, Barbara, et al.
Publicado: (2021)

Genetic risk for Alzheimer’s disease influences neuropathology via multiple biological pathways
por: Hannon, Eilis, et al.
Publicado: (2020)

The contribution of neuropathology to multiple sclerosis research
por: Lassmann, Hans
Publicado: (2022)

Editorial: Contribution of ion channels to neuropathologies
por: Kecskes, Miklos, et al.
Publicado: (2023)

Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change
por: Smirnov, Denis S., et al.
Publicado: (2022)

Microglia in Alzheimer Brain: A Neuropathological Perspective
por: Mrak, Robert E.
Publicado: (2012)

Alzheimer disease neuropathology: understanding autonomic dysfunction
por: Engelhardt, Eliasz, et al.
Publicado: (2008)

Neuropathological Mechanisms Associated with Pesticides in Alzheimer’s Disease
por: Tang, Bor Luen
Publicado: (2020)

Progranulin mutations in clinical and neuropathological Alzheimer's disease
por: Vardarajan, Badri N., et al.
Publicado: (2022)

Cognitive resilience and severe Alzheimer’s disease neuropathology
por: Ahangari, Narges, et al.
Publicado: (2023)

Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer’s Disease
por: Zhang, Zhong-Hao, et al.
Publicado: (2016)

Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model
por: Guo, Chuang, et al.
Publicado: (2016)

Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer’s disease
por: Reas, Emilie T., et al.
Publicado: (2017)

Lipids and lipoproteins may play a role in the neuropathology of Alzheimer’s disease
por: Akyol, Omer, et al.
Publicado: (2023)

Complement Nomenclature—Deconvoluted
por: Bohlson, Suzanne S., et al.
Publicado: (2019)

VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology
por: Wen, Lei, et al.
Publicado: (2011)

The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia
por: Tasaki, Shinya, et al.
Publicado: (2018)

Association of Neighborhood-Level Disadvantage With Alzheimer Disease Neuropathology
por: Powell, W. Ryan, et al.
Publicado: (2020)

Plasmalogen deficiency and neuropathology in Alzheimer's disease: Causation or coincidence?
por: Senanayake, Vijitha, et al.
Publicado: (2019)

Hospitalization, Alzheimer's Disease and Related Neuropathologies, and Cognitive Decline
por: James, Bryan D., et al.
Publicado: (2019)

The Cholinergic System, the Adrenergic System and the Neuropathology of Alzheimer’s Disease
por: Bekdash, Rola A.
Publicado: (2021)

Neuropathology of the Brainstem to Mechanistically Understand and to Treat Alzheimer’s Disease
por: Patthy, Ágoston, et al.
Publicado: (2021)

Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes
por: Uretsky, Madeline, et al.
Publicado: (2021)

Cognitive reserve, neuropathology, and progression towards Alzheimer’s disease
por: Nelson, Monica E., et al.
Publicado: (2023)

Effect of canola oil consumption on memory, synapse and neuropathology in the triple transgenic mouse model of Alzheimer’s disease
por: Lauretti, Elisabetta, et al.
Publicado: (2017)

A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model
por: Ortí-Casañ, Natalia, et al.
Publicado: (2022)

The behavioural and neuropathologic sexual dimorphism and absence of MIP-3α in tau P301S mouse model of Alzheimer’s disease
por: Sun, Yao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m146br8duki2nvvtpff310kpcf