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Transcription and Translation Products of the Cytolysin Gene psm-mec on the Mobile Genetic Element SCCmec Regulate Staphylococcus aureus Virulence

The F region downstream of the mecI gene in the SCCmec element in hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) contains two bidirectionally overlapping open reading frames (ORFs), the fudoh ORF and the psm-mec ORF. The psm-mec ORF encodes a cytolysin, phenol-soluble modu...

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Detalles Bibliográficos
Autores principales: Kaito, Chikara, Saito, Yuki, Nagano, Gentaro, Ikuo, Mariko, Omae, Yosuke, Hanada, Yuichi, Han, Xiao, Kuwahara-Arai, Kyoko, Hishinuma, Tomomi, Baba, Tadashi, Ito, Teruyo, Hiramatsu, Keiichi, Sekimizu, Kazuhisa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033363/
https://www.ncbi.nlm.nih.gov/pubmed/21304931
http://dx.doi.org/10.1371/journal.ppat.1001267