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Gene Expression Noise in Spatial Patterning: hunchback Promoter Structure Affects Noise Amplitude and Distribution in Drosophila Segmentation

Positional information in developing embryos is specified by spatial gradients of transcriptional regulators. One of the classic systems for studying this is the activation of the hunchback (hb) gene in early fruit fly (Drosophila) segmentation by the maternally-derived gradient of the Bicoid (Bcd)...

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Detalles Bibliográficos
Autores principales: Holloway, David M., Lopes, Francisco J. P., da Fontoura Costa, Luciano, Travençolo, Bruno A. N., Golyandina, Nina, Usevich, Konstantin, Spirov, Alexander V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033364/
https://www.ncbi.nlm.nih.gov/pubmed/21304932
http://dx.doi.org/10.1371/journal.pcbi.1001069