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Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

Refolding of viral class-1 membrane fusion proteins from a native state to a trimer-of-hairpins structure promotes entry of viruses into cells. Here we present the structure of the bovine leukaemia virus transmembrane glycoprotein (TM) and identify a group of asparagine residues at the membrane-dist...

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Detalles Bibliográficos
Autores principales: Lamb, Daniel, Schüttelkopf, Alexander W., van Aalten, Daan M. F., Brighty, David W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033372/
https://www.ncbi.nlm.nih.gov/pubmed/21304939
http://dx.doi.org/10.1371/journal.ppat.1001268