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Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins
Refolding of viral class-1 membrane fusion proteins from a native state to a trimer-of-hairpins structure promotes entry of viruses into cells. Here we present the structure of the bovine leukaemia virus transmembrane glycoprotein (TM) and identify a group of asparagine residues at the membrane-dist...
Autores principales: | Lamb, Daniel, Schüttelkopf, Alexander W., van Aalten, Daan M. F., Brighty, David W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033372/ https://www.ncbi.nlm.nih.gov/pubmed/21304939 http://dx.doi.org/10.1371/journal.ppat.1001268 |
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