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Entrapment of Viral Capsids in Nuclear PML Cages Is an Intrinsic Antiviral Host Defense against Varicella-Zoster Virus

The herpesviruses, like most other DNA viruses, replicate in the host cell nucleus. Subnuclear domains known as promyelocytic leukemia protein nuclear bodies (PML-NBs), or ND10 bodies, have been implicated in restricting early herpesviral gene expression. These viruses have evolved countermeasures t...

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Detalles Bibliográficos
Autores principales: Reichelt, Mike, Wang, Li, Sommer, Marvin, Perrino, John, Nour, Adel M., Sen, Nandini, Baiker, Armin, Zerboni, Leigh, Arvin, Ann M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033373/
https://www.ncbi.nlm.nih.gov/pubmed/21304940
http://dx.doi.org/10.1371/journal.ppat.1001266