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Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

Influenza A virus pandemics and emerging anti-viral resistance highlight the urgent need for novel generic pharmacological strategies that reduce both viral replication and lung inflammation. We investigated whether the primary enzymatic source of inflammatory cell ROS (reactive oxygen species), Nox...

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Detalles Bibliográficos
Autores principales: Vlahos, Ross, Stambas, John, Bozinovski, Steven, Broughton, Brad R. S., Drummond, Grant R., Selemidis, Stavros
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033375/
https://www.ncbi.nlm.nih.gov/pubmed/21304882
http://dx.doi.org/10.1371/journal.ppat.1001271