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Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance

How epigenetic information is propagated during somatic cell divisions is still unclear but is absolutely critical for preserving gene expression patterns and cellular identity. Here we show an unanticipated mechanism for inheritance of DNA methylation patterns where the epigenetic mark not only rec...

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Detalles Bibliográficos
Autores principales: Sharma, Shikhar, De Carvalho, Daniel D., Jeong, Shinwu, Jones, Peter A., Liang, Gangning
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033376/
https://www.ncbi.nlm.nih.gov/pubmed/21304883
http://dx.doi.org/10.1371/journal.pgen.1001286