A New Testing Strategy to Identify Rare Variants with Either Risk or Protective Effect on Disease

Rapid advances in sequencing technologies set the stage for the large-scale medical sequencing efforts to be performed in the near future, with the goal of assessing the importance of rare variants in complex diseases. The discovery of new disease susceptibility genes requires powerful statistical m...

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Detalles Bibliográficos
Autores principales: Ionita-Laza, Iuliana, Buxbaum, Joseph D., Laird, Nan M., Lange, Christoph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033379/
https://www.ncbi.nlm.nih.gov/pubmed/21304886
http://dx.doi.org/10.1371/journal.pgen.1001289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033379/
https://www.ncbi.nlm.nih.gov/pubmed/21304886
http://dx.doi.org/10.1371/journal.pgen.1001289

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