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Interferon Gamma-Dependent Intestinal Pathology Contributes to the Lethality in Bacterial Superantigen-Induced Toxic Shock Syndrome

Toxic shock syndrome (TSS) caused by the superantigen exotoxins of Staphylococcus aureus and Streptococcus pyogenes is characterized by robust T cell activation, profound elevation in systemic levels of multiple cytokines, including interferon-γ (IFN-γ), followed by multiple organ dysfunction and of...

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Detalles Bibliográficos
Autores principales: Tilahun, Ashenafi Y., Holz, Marah, Wu, Tsung-Teh, David, Chella S., Rajagopalan, Govindarajan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033413/
https://www.ncbi.nlm.nih.gov/pubmed/21304813
http://dx.doi.org/10.1371/journal.pone.0016764