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Inhibition of Hedgehog Signaling Decreases Proliferation and Clonogenicity of Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSC) have the ability to differentiate into osteoblasts, adipocytes and chondrocytes. We have previously shown that hMSC were endowed with a basal level of Hedgehog signaling that decreased after differentiation of these cells. Since hMSC differentiation is associated...

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Detalles Bibliográficos
Autores principales: Plaisant, Magali, Giorgetti-Peraldi, Sophie, Gabrielson, Marike, Loubat, Agnes, Dani, Christian, Peraldi, Pascal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033417/
https://www.ncbi.nlm.nih.gov/pubmed/21304817
http://dx.doi.org/10.1371/journal.pone.0016798