GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation

PURPOSE: The purpose of this review is to summarize current knowledge of detailed biochemical evidence for the role of γ-aminobutyric acid type A receptors (GABA(A)–Rs) in the mechanisms of general anesthesia. PRINCIPAL FINDINGS: With the knowledge that all general anesthetics positively modulate GA...

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Detalles Bibliográficos
Autores principales: Olsen, Richard W., Li, Guo-Dong
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Theme Issue: Mechanisms of Anesthesia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033524/
https://www.ncbi.nlm.nih.gov/pubmed/21194017
http://dx.doi.org/10.1007/s12630-010-9429-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033524/
https://www.ncbi.nlm.nih.gov/pubmed/21194017
http://dx.doi.org/10.1007/s12630-010-9429-7

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