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GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation
PURPOSE: The purpose of this review is to summarize current knowledge of detailed biochemical evidence for the role of γ-aminobutyric acid type A receptors (GABA(A)–Rs) in the mechanisms of general anesthesia. PRINCIPAL FINDINGS: With the knowledge that all general anesthetics positively modulate GA...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033524/ https://www.ncbi.nlm.nih.gov/pubmed/21194017 http://dx.doi.org/10.1007/s12630-010-9429-7 |