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Increased Selectivity, Analytical Precision, and Throughput in Targeted Proteomics

Proteomics is gradually complementing large shotgun qualitative studies with hypothesis-driven quantitative experiments. Targeted analyses performed on triple quadrupole instruments in selected reaction monitoring mode are characterized by a high degree of selectivity and low limit of detection; how...

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Detalles Bibliográficos
Autores principales: Kiyonami, Reiko, Schoen, Alan, Prakash, Amol, Peterman, Scott, Zabrouskov, Vlad, Picotti, Paola, Aebersold, Ruedi, Huhmer, Andreas, Domon, Bruno
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033677/
https://www.ncbi.nlm.nih.gov/pubmed/20664071
http://dx.doi.org/10.1074/mcp.M110.002931