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Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging

The biological process of aging is believed to be the result of an accumulation of cellular damage to biomolecules. Although there are numerous studies addressing mutation frequencies, morphological or transcriptional changes in aging mammalian tissues, few have measured global changes at the protei...

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Detalles Bibliográficos
Autores principales: Walther, Dirk M., Mann, Matthias
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033683/
https://www.ncbi.nlm.nih.gov/pubmed/21048193
http://dx.doi.org/10.1074/mcp.M110.004523