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Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging
The biological process of aging is believed to be the result of an accumulation of cellular damage to biomolecules. Although there are numerous studies addressing mutation frequencies, morphological or transcriptional changes in aging mammalian tissues, few have measured global changes at the protei...
Autores principales: | Walther, Dirk M., Mann, Matthias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033683/ https://www.ncbi.nlm.nih.gov/pubmed/21048193 http://dx.doi.org/10.1074/mcp.M110.004523 |
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