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Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV

BACKGROUND: We have evaluated an attenuated Listeria monocytogenes (Lm) candidate vaccine vector in nonhuman primates using a delivery regimen relying solely on oral vaccination. We sought to determine the impact of prior Lm vector exposure on the development of new immune responses against HIV anti...

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Detalles Bibliográficos
Autores principales: Whitney, James B, Mirshahidi, Saied, Lim, So-Yon, Goins, Lauren, Ibegbu, Chris C, Anderson, Daniel C, Raybourne, Richard B, Frankel, Fred R, Lieberman, Judy, Ruprecht, Ruth M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033796/
https://www.ncbi.nlm.nih.gov/pubmed/21244649
http://dx.doi.org/10.1186/1476-8518-9-2