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Pathway-based analysis using reduced gene subsets in genome-wide association studies

BACKGROUND: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to small marginal effects. Pathway level analysis incorporating prior biological information offers another way to analyze GW...

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Detalles Bibliográficos
Autores principales: Zhao, Jingyuan, Gupta, Simone, Seielstad, Mark, Liu, Jianjun, Thalamuthu, Anbupalam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033801/
https://www.ncbi.nlm.nih.gov/pubmed/21226955
http://dx.doi.org/10.1186/1471-2105-12-17