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Identification of critical residues of influenza neuraminidase in viral particle release

BACKGROUND: Influenza neuraminidase (NA) is essential for virus release from its host cells and it is one of the targets for structure-based antiviral drug design. RESULTS: In this report, we established a pseudoviral particle release assay to study NA function, which is based on lentiviral particle...

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Detalles Bibliográficos
Autores principales: Tisoncik, Jennifer R, Guo, Ying, Cordero, Katie S, Yu, Jia, Wang, Jianwei, Cao, Youjia, Rong, Lijun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033838/
https://www.ncbi.nlm.nih.gov/pubmed/21232128
http://dx.doi.org/10.1186/1743-422X-8-14