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Prolyl Isomerase Pin1 Protects Mice from Endotoxin Shock

BACKGROUND: Prolyl isomerase Pin1 may be involved in innate immunity against microbial infection, but the mechanism how Pin1 controls the innate immunity is poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: Injection of lipopolysaccharide (LPS) into the mice induces inflammatory pulmonary disorder...

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Detalles Bibliográficos
Autores principales: Akiyama, Hirotada, Misawa, Takuma, Ono, Masao, Uchida, Chiyoko, Uchida, Takafumi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033895/
https://www.ncbi.nlm.nih.gov/pubmed/21326608
http://dx.doi.org/10.1371/journal.pone.0014656