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Chemogenomic Analysis of G-Protein Coupled Receptors and Their Ligands Deciphers Locks and Keys Governing Diverse Aspects of Signalling

Understanding the molecular mechanism of signalling in the important super-family of G-protein-coupled receptors (GPCRs) is causally related to questions of how and where these receptors can be activated or inhibited. In this context, it is of great interest to unravel the common molecular features...

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Detalles Bibliográficos
Autores principales: Wichard, Jörg D., ter Laak, Antonius, Krause, Gerd, Heinrich, Nikolaus, Kühne, Ronald, Kleinau, Gunnar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033908/
https://www.ncbi.nlm.nih.gov/pubmed/21326864
http://dx.doi.org/10.1371/journal.pone.0016811