ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

Ataxia telangiectasia (A-T) is a human disease caused by ATM deficiency characterized among other symptoms by radiosensitivity, cancer, sterility, immunodeficiency and neurological defects. ATM controls several aspects of cell cycle and promotes repair of double strand breaks (DSBs). This probably a...

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Detalles Bibliográficos
Autores principales: Cosentino, Claudia, Grieco, Domenico, Costanzo, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034007/
https://www.ncbi.nlm.nih.gov/pubmed/21157431
http://dx.doi.org/10.1038/emboj.2010.330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034007/
https://www.ncbi.nlm.nih.gov/pubmed/21157431
http://dx.doi.org/10.1038/emboj.2010.330

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