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ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
Ataxia telangiectasia (A-T) is a human disease caused by ATM deficiency characterized among other symptoms by radiosensitivity, cancer, sterility, immunodeficiency and neurological defects. ATM controls several aspects of cell cycle and promotes repair of double strand breaks (DSBs). This probably a...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034007/ https://www.ncbi.nlm.nih.gov/pubmed/21157431 http://dx.doi.org/10.1038/emboj.2010.330 |