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CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype

BACKGROUND AND AIMS: Intestinal metaplasia (IM) is a gastric preneoplastic lesion that appears following Helicobacter pylori infection and confers an increased risk for development of cancer. It is induced by gastric expression of the intestine-specific transcription factor CDX2. The regulatory mech...

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Detalles Bibliográficos
Autores principales: Barros, Rita, da Costa, Luis Teixeira, Pinto-de-Sousa, João, Duluc, Isabelle, Freund, Jean-Noel, David, Leonor, Almeida, Raquel
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034084/
https://www.ncbi.nlm.nih.gov/pubmed/21148572
http://dx.doi.org/10.1136/gut.2010.222323