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Opposing function of mitochondrial prohibitin in aging

While specific signalling cascades involved in aging, such as the insulin/IGF-1 pathway, are well-described, the actual metabolic changes they elicit to prolong lifespan remain obscure. Nevertheless, the tuning of cellular metabolism towards maximal survival is the molecular basis of longevity. The...

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Detalles Bibliográficos
Autores principales: Artal-Sanz, Marta, Tavernarakis, Nektarios
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034168/
https://www.ncbi.nlm.nih.gov/pubmed/21164222