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Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells
Long INterspersed Element-1 (LINE-1 or L1) retrotransposition continues to impact human genome evolution1,2. L1s can retrotranspose in the germline, during early development, and in select somatic cells3,4,5,6,7,8; however, the host response to L1 retrotransposition remains largely unexplored. Here,...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034402/ https://www.ncbi.nlm.nih.gov/pubmed/20686575 http://dx.doi.org/10.1038/nature09209 |